But treatmenttherapy, medicine, or bothis usually very effective. Topics include etiology, pathogenesis, management, and prevention of diabetes, as well as associated complications such as nephropathy. Estimates of diabetes and its burden in the united states, 2014. Insulin is a hormone that helps the glucose get into your cells to give them energy. It provides clinicians with the latest findings and opinions on the optimum therapies to check the ever expanding diabetes. Diabetes is a name given to the distinct conditions in which there is a large amount of glucose in the blood and it is the ability of the body to. Type 2 diabetes is much more common and accounts for 9095% of all diabetes. Developing nonalcoholic fatty liver disease, or nafld, occurs in people with obesity and type 2 diabetes, and can be reversed with weight loss. Type 1 diabetes accounts for 80%90% of diabetes in children and adolescents2,26. Topics include etiology, pathogenesis, management, and prevention of diabetes, as well as associated complications. Diabetes is a serious, chronic disease that occurs either when the pancreas does not produce enough insulin a hormone that regulates blood sugar, or glucose, or when the body cannot effectively use the insulin it. Diabetes type 1 diabetes type 2 diabetes medlineplus. Type 2 diabetes primarily affects adults, however recently type 2 has begun developing in children.
T2dm is the most common form of dm, which accounts for 90% to 95% of all diabetic patients 1 and is expected to increase to 439 million by 2030 in 2. Diabetes in older adults is a growing public health burden. This type of diabetes constitutes 5%10% of subjects diagnosed with diabetes and is due to destruction of. Feb 21, 2014 to prevent, delay, and treat diabetesrelated complications. Obesity is one of the major causes of type 2 diabetes.
Diabetes is a chronic condition associated with abnormally high levels of sugar glucose in the blood. Type 1 diabetes, also called insulin dependent diabetes mellitus iddm, is caused by lack of insulin secretion by beta. Journal of metabolic syndrome publishes the articles related to diabetes. About 1 in every 7 people with type 1 diabetes has a condition called type 2 polyglandular autoimmune syndrome. The prevalence of diabetes in the who african region was estimated in 2000 to be at 7. There does appear to be a genetic component to type 1 diabetes, but the cause has yet to be identified. Of impending concern is that these numbers are projected to grow dramatically over the next few decades 1,2.
The attempts to adhere to the conventional food measurements in order to comply with prescriptions of the socalled diabetic diet usually result in unnecessary restrictions, overindulgence, or monotonous consumption of certain food. Diabetes mellitus a devastating metabolic disorder. While metformin remains firstline treatment for type 2 diabetes, there are now two classes of medications to improve diabetes outcomes. Aug 06, 2018 people with diabetes are 2 to 3 times more likely to have depression than people without diabetes.
Diabetes the solution prevention without urgent action, diabetesrelated deaths will increase by more than 50% in the next 10 years. Diabetes articles breastfeeding may protect highrisk women from diabetes later in life breastfeeding may reduce diabetes risk in women who experienced gestational diabetes during pregnancy. Please use one of the following formats to cite this article in your essay, paper or report. Diabetes journal diabetes mellitus journal open access. Pdf diabetes mellitus and related oral manifestations. Congenital generalized lipodystrophy cgl is a rare disorder.
Journal of diabetes and its complications jdc is a journal for health care practitioners and researchers, that publishes original research about the pathogenesis, diagnosis and management of diabetes mellitus and its complications. The prevention and control the type2 diabetes by changing. The current study used national nationwide inpatient sample nis data for assessing the trends in diabetes related. Be physically active at least 30 minutes of regular, moderateintensity activity on most days. Type 1 diabetes mellitus t1dm is a chronic, lifelong disorder of glucose homeostasis characterized by autoimmune destruction of the insulinproducing pancreatic bcell, leading progressively to. Accepted 16 april, 2009 diabetes is a lifelong disease marked by elevated levels of sugar in the blood. Publication trends of research on diabetes mellitus and t cells plos. The most downloaded articles from journal of diabetes and its complications in the last 90 days. The number of people with diabetes is expected to rise to 592 million by 2035. More the high cost of a poor diet what people choose to eat has a big impact on their cardiovascular health. Insulin resistance, type 1 and type 2 diabetes, and related. Perspectives in diabetes history of diabetes, the journal 1. Most downloaded journal of diabetes and its complications articles.
Insulin produced by the pancreas lowers blood glucose. About 50% of patients are thought to be undiagnosed. Diabetes symptoms vary depending on how much your blood sugar is elevated. Review article diabetes mellitus a devastating metabolic. The global escalation of obesity and diabetes in developed and developing nations poses a great health challenge. Osteoporosis is a bone condition defined by low bone mass, increased fragility, decreased bone quality, and an increased fracture risk. Trends in diabetesrelated preventable hospitalizations in. Most downloaded diabetes research and clinical practice articles. With type 2 diabetes, the more common type, your body does not make or use. Study of the effect of glycemic control on the diabetes related distress in a sample of egyptian patients with diabetes mellitus. Screening and diagnosis is still based on world health organization who and american diabetes association ada. Dietary and nutritional approaches for prevention and.
Jdc also publishes articles on physiological and molecular aspects of glucose homeostasis. Only 25% to 50% of people with diabetes who have depression get diagnosed and treated. Tenyear followup of diabetes incidence and weight loss in the diabetes prevention program outcomes study. Review risk factors contributing to type 2 diabetes and. Results from the international diabetes federation diabetes. While rates of diabetesrelated complications have declined overall in the general population, the incidence rates of macrovascular complications such as acute myocardial infarction and stroke continue to be the highest in older agegroups. The challenges related to blood glucose management vary with diabetes type, activity type, and presence of diabetes related complications 5,6.
Get examples of generic and name brand medications. Citescore values are based on citation counts in a given year e. May 28, 2019 current guidelines also recommend using one of the following if a person with type 2 diabetes has a high risk of atherosclerotic cardiovascular disease, diabetes related kidney disease, or both. Absence or insufficient production of insulin, or an inability of the body to properly use insulin causes diabetes. Diabetes related preventable hospitalizations are indicators of effective primary care services 1, but recent trends are unknown. Nerve damage from diabetes is called diabetic neuropathy newropuhthee.
Articles journal of diabetes research and clinical metabolism. Most of the food you eat is broken down into sugar also called glucose and released into. To find a diabetes educator contact the american association of diabetes educators at 8008326874. Both are caused by problems making or using insulin, a. Diabetes is a condition that impairs the bodys ability to process blood glucose, otherwise known as blood sugar. Obesity and diabetes medical news medical articles. If both you and your partner have type 1 diabetes, the risk is between 1 in 10 and 1 in 4. The three types are type 1, type 2, and gestational diabetes. China, the latest statistical data that diabetes show and pre diabetes.
Unusual clinical features associated with congenital generalized lipodystrophy type 4 in a patient with a novel e211x cavin1 gene variant. Most downloaded diabetes research and clinical practice. Diabetes mellitus, commonly known as diabetes, is a metabolic disease that causes high blood sugar. Diabetes mellitus samreen riaz department of microbiology and molecular genetics, punjab university, new campus, lahore. People with diabetes are 2 to 3 times more likely to have depression than people without diabetes. Hence, we examined the trends in diabetesrelated preventable hospitalizations to critically inform policy decisions seeking accountability. Diabetes is a progressive disease, and the treatment may change over time, requiring oral medication. In the united states, the estimated number of people over 18 years of age with. To prevent, delay, and treat diabetesrelated complications. Diabetes is a serious, chronic disease that occurs either when the pancreas does not produce enough insulin a hormone that regulates blood sugar, or glucose, or when the body cannot effectively use the. To help prevent type 2 diabetes and its complications, people should.
Jan 09, 2020 diabetes is a condition that impairs the bodys ability to process blood glucose, otherwise known as blood sugar. Education and diabetes mellitus health science journals. Jun, 2018 common ground on dietary approaches for the prevention, management, and potential remission of type 2 diabetes can be found, argue nita g forouhi and colleagues dietary factors are of paramount importance in the management and prevention of type 2 diabetes. The most downloaded articles from diabetes research and clinical practice in the last 90 days. Despite progress in formulating evidence based dietary guidance, controversy and confusion remain. And without treatment, depression often gets worse, not better. The incidence of type 2 diabetes, which is the most prevalent form of diabetes, is increasing to nearepidemic levels in industrialized countries. Recent diabetes research and clinical practice articles. A diabetes medication used for people with type 2 diabetes, biguanides help lower blood glucose level. Diabetes is a chronic longlasting health condition that affects how your body turns food into energy. The prognosis of diabetes is related to the extent to which the condition is kept under control to prevent the development of the complications described in the preceding sections. The hormone insulin moves sugar from the blood into your cells to be stored or used for. In addition, close to 1,100 people died from diabetes related causes. Metabolic abnormalities in carbohydrates, lipids, and proteins result from the importance of insulin as an anabolic hormone.
To put the advent of diabetes into historical persepctive, diabetes began in the same year. Insulin resistance, type 1 and type 2 diabetes, and. Jun 25, 2015 diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Pdf diabetes mellitus dm also known as simply diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged. The attempts to adhere to the conventional food measurements in order to comply. Low levels of insulin to achieve adequate response andor. The unprecedented aging of the worlds population is a major contributor to the diabetes epidemic, and older adults represent one of the fastest growing segments of the diabetes population. Articles submitted to jdbt can report any aspect of basic. Risk factors for type 1 diabetes are not as clear as for prediabetes and type 2 diabetes. One in 3 people in the us will develop fatty liver disease. Keep your risk of glaucoma, cataracts and other eye problems low with regular checkups.
The disease expected to take dimensions of an epidemic is often called the scourge of modern times. Metformin as firstline treatment for type 2 diabetes. Having a parent, brother, or sister with type 1 diabetes. With type 1 diabetes, your body does not make insulin. Type 1 diabetes, also called insulin dependent diabetes. It is the second leading cause of blindness and renal disease worldwide. Table of contents journal of diabetes research hindawi. Some people, especially those with prediabetes or type 2 diabetes, may not experience symptoms initially. In type 1 diabetes, symptoms tend to come on quickly and be more severe. Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetes is a condition that affects the bodys ability to use blood sugar for energy. Regular exercise also has considerable health benefits for people with type 1 diabetes e. These individuals also have the highest rate of diabetesrelated endstage renal disease. Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high.
Type 1 diabetes is primarily due to the autoimmunemediated destruction of pancreatic beta cell leading to insulin deficiency. Some of the more serious complications of diabetes such as kidney failure and cardiovascular disease, can be lifethreatening. Diabetes overall at least doubles the risk of death. According to international diabetes federation idf, the number of youth 014 years diagnosed with type 1 diabetes worldwide in 20 was. Journal of diabetes research publishes articles related to type 1 and type 2 diabetes. Type 1 diabetes is thought to be caused by an immune reaction the body attacks itself by mistake. We read with interest the letter by remy boussageon and colleagues1 march 31, p 1261 discussing the certainty of evidence for metformin as firstline treatment for type 2 diabetes, in response to a seminar by sudesna chatterjee and colleagues. Stay alert for symptoms of skin infections and other skin disorders common in people with diabetes.